CHEM - Faculty Positions

HK University of Science & Technology

Duties & Responsibilities

Establish and lead a state-of-the-art deep proteomics and interactomics capability centered on proteome-wide crosslinking mass spectrometry (XL-MS).
Define and oversee purchase, installation and commissioning of mass spectrometry instrumentation, sample-preparation infrastructure and computing resources.
Develop, optimize and set up workflows for quantitative proteomics, crosslinking MS, spatial proteomics and protein-protein interaction mapping with associated data-analysis pipelines.
Develop new methods in proteomics and XL-MS and publish them in leading international journals.
Plan and run collaborative research projects with faculty across the institution in areas including membrane trafficking, autophagy, neurobiology, and stem cell research.
Train and supervise research staff, postdoctoral fellows and research students in proteomics and XL-MS methods.

PhD in biochemistry, analytical chemistry, molecular biology or related field with at least 10 years of postdoctoral and independent research experience.
Internationally recognized expertise in developing crosslinking mass spectrometry methods covering crosslinker chemistry, sample preparation, MS acquisition and/or computational analysis.
Proven record of high-impact methods development publications as first and senior/corresponding author in leading journals.
Extensive hands-on experience with high-resolution Orbitrap-class mass spectrometers, nano-LC systems and large-scale proteomic data analysis.
Experience independently leading a research group and/or managing a mass spectrometry or proteomics core facility including instrument and workflow setup.
Record of successful interdisciplinary collaborations applying proteomics to cell biology, structural biology or neuroscience questions.